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Tadalafil Tablet

 

 

Tadalafil is used to treat male sexual function problems (impotence or erectile dysfunction-ED). In combination with sexual stimulation, tadalafil works by increasing blood flow to the penis to help a man get and keep an erection.Tadalafil is also used to treat the symptoms of an enlarged prostate (benign prostatic hyperplasia-BPH).

It helps to relieve symptoms of BPH such as difficulty in beginning the flow of urine, weak stream, and the need to urinate frequently or urgently (including during the middle of the night).

Tadalafil is thought to work by relaxing the smooth muscle in the prostate and bladder.This drug does not protect against sexually transmitted diseases (such as HIV, hepatitis B, gonorrhea, syphilis). 

 

 

 

 

 

  • Indications
  • Mechanism of action
  • side effects
  • Drug interactions
  • Warnings
  • Use in pregnancy and breastfeeding
  • نظرات

Tadalafil is a medication used for erectile dysfunction (ED), helping men achieve and maintain erections, as well as for treating symptoms of benign prostatic hyperplasia (BPH), improving urinary difficulties. In some cases, it is prescribed for pulmonary arterial hypertension (PAH) to manage high blood pressure in the lung arteries. The medication should be taken under the guidance of a healthcare professional, and it is not intended for use in women

Tadalafil works by inhibiting the enzyme PDE5, which usually breaks down cyclic guanosine monophosphate (cGMP). During sexual stimulation, nitric oxide is released, leading to increased cGMP production. Elevated cGMP levels cause relaxation of smooth muscles in the penis and increased blood flow, facilitating an erection. Tadalafil's action in blocking PDE5 prolongs the presence of cGMP, maintaining smooth muscle relaxation and promoting sustained erections. This mechanism is effective in treating erectile dysfunction (ED) and, to some extent, in managing symptoms of benign prostatic hyperplasia (BPH) and pulmonary arterial hypertension (PAH).

Common side effects of Tadalafil include headache, flushing, upset stomach, back pain, muscle aches, nasal congestion, vision changes, and dizziness. Priapism, a prolonged and painful erection, is a rare but serious side effect. It's important to seek medical advice for persistent or severe side effects. Individuals with pre-existing conditions, especially cardiovascular issues, should use Tadalafil with caution and consult with a healthcare professional for personalized guidance

Tadalafil can interact with several medications, including nitrates, alpha-blockers, antihypertensive drugs, CYP3A4 inhibitors, and inducers, as well as other PDE5 inhibitors. Combining Tadalafil with nitrates is contraindicated due to the risk of severe hypotension. Additionally, grapefruit juice can increase Tadalafil levels. It's essential to inform healthcare providers about all medications and consult for personalized advice to avoid potential interactions and adjust treatment regimens based on individual health conditions

Tadalafil warnings include cardiovascular risks, the potential for priapism (prolonged erection), rare cases of vision and hearing loss, caution with hypotension, interactions with various medications, and considerations for individuals with pre-existing conditions. Tadalafil is not intended for use in women, and the safety during pregnancy and breastfeeding is not well established. Consultation with a healthcare professional is crucial for personalized assessment and guidance

Tadalafil is generally not recommended during pregnancy and breastfeeding due to limited data on safety. In pregnancy, the decision should involve a thorough risk-benefit assessment by a healthcare provider. For breastfeeding, caution is advised as Tadalafil is excreted into breast milk, and the effects on the nursing infant are not well studied. Alternative medications with more established safety profiles may be considered. Individual consultations with healthcare professionals are crucial to make informed decisions based on specific circumstances

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Tadalafil Tablet
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